Bone and soft tissue regenerative therapies. which are the future perspectives?
Dental implants are the treatment of choice in the majority of the edentulism. A significant lack of volume in the alveolar ridge (hard and soft tissue), compromises the final prosthetic restorations from an aesthetic as well as functional point of view. To recovery this lost volume, tissue engineering is the treatment of choice and is based on three pillars: cells, scaffold, and biomolecules. Currently, there are several possibilities to deal with this technique, being guided bone regeneration (GBR), the use of bone blocks, and connective tissue autografts, the most scientifically approved to be used in daily practice. However, the clinical application of bone and soft tissue substitutes is increasing due to the scientific and clinical evidence improving. Customized augmenting bone block materials is currently an emerging field in dental implant surgery. Originating from humans (allogenic) todays’ digital workflow can emerge CAD-CAM blocks fitting precisely into the defect situation and therefore reduce operation time. Moreover, new acellular dermal matrices as soft tissue substitutes are emerging and providing promising results.
In this conference we will update the scientific evidence of using CAD-CAM allografts and a new acellular dermal matrix, showing preliminary data of our own research and several cases in different clinical scenarios.